PRPF18 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
PRPF18 Peptide Applications :
Blocking Background :
PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10. Alternative Name :
Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18; PRP18; HPRP18 Swiss-Prot :
Q99633 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PRPF18. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5866 PRPF18 pAb.
PRPF18 Peptide Applications :
Blocking Background :
PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing. A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms which are encoded by a gene located on human chromosome 10p13. Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency and trisomy 10. Alternative Name :
Pre-mRNA-splicing factor 18; PRP18 homolog; hPRP18; PRP18; HPRP18 Swiss-Prot :
Q99633 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide PRPF18. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5866 PRPF18 pAb.
Blocking peptide available as BS5866PP