ORC1 Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
ORC1 Peptide Applications :
Blocking Background :
ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells. Alternative Name :
Origin recognition complex subunit 1; Replication control protein 1; ORC1L; PARC1 Swiss-Prot :
Q13415 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ORC1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5836 ORC1 pAb.
ORC1 Peptide Applications :
Blocking Background :
ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors. Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis. ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin. ORC4 and ORC6 are also expressed constantly throughout the cell cycle. ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble. The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells. Alternative Name :
Origin recognition complex subunit 1; Replication control protein 1; ORC1L; PARC1 Swiss-Prot :
Q13415 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide ORC1. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5836 ORC1 pAb.
Blocking peptide available as BS5836PP