Na+ CP type IXα Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Na+ CP type IXα Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IXα, also known as SCN9A (sodium channel protein type 9 subunit α), NENA, PN1, Nav1.7 or ETHA, is a 1,988 amino acid multi-pass membrane protein that belongs to the voltage-gated sodium channel family. Expressed in dorsal root ganglion, smooth muscle cells and in the central and peripheral nervous system, Na+ CP type IXα functions to mediate the voltage-dependent sodium ion permeability of membranes, specifically forming a sodium-selective ion channel through which sodium may pass. Via its ability to control the flow of sodium in and out of excitable membranes, Na+ CP type IXα plays an important role in the inflammatory pain response. Defects in the gene encoding Na+ CP type IXα are the cause of primary erythermalgia, autosomal recessive congenital indifference to pain and paroxysmal extreme pain disorder (PEPD), all of which are genetic pain disorders. Alternative Name :
Sodium channel protein type 9 subunit alpha; Neuroendocrine sodium channel; hNE-Na; Peripheral sodium channel 1; PN1; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7; SCN9A; NENA Swiss-Prot :
Q15858 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IXα. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5813 Na+ CP type IXα pAb.
Na+ CP type IXα Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IXα, also known as SCN9A (sodium channel protein type 9 subunit α), NENA, PN1, Nav1.7 or ETHA, is a 1,988 amino acid multi-pass membrane protein that belongs to the voltage-gated sodium channel family. Expressed in dorsal root ganglion, smooth muscle cells and in the central and peripheral nervous system, Na+ CP type IXα functions to mediate the voltage-dependent sodium ion permeability of membranes, specifically forming a sodium-selective ion channel through which sodium may pass. Via its ability to control the flow of sodium in and out of excitable membranes, Na+ CP type IXα plays an important role in the inflammatory pain response. Defects in the gene encoding Na+ CP type IXα are the cause of primary erythermalgia, autosomal recessive congenital indifference to pain and paroxysmal extreme pain disorder (PEPD), all of which are genetic pain disorders. Alternative Name :
Sodium channel protein type 9 subunit alpha; Neuroendocrine sodium channel; hNE-Na; Peripheral sodium channel 1; PN1; Sodium channel protein type IX subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.7; SCN9A; NENA Swiss-Prot :
Q15858 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IXα. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5813 Na+ CP type IXα pAb.
Blocking peptide available as BS5813PP