Na+ CP type IIβ Peptide 
Datasheet
COA
MSDS
SHIP
Product Name :
Na+ CP type IIβ Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IIβ (sodium channel, voltage-gated, typeII, β), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type IIβ contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2. Alternative Name :
Sodium channel subunit beta-2; SCN2B; ORF Names: UNQ326/PRO386; Na+ CP typeIIβ Swiss-Prot :
O60939 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IIβ. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5811 Na+ CP type IIβ pAb.
Na+ CP type IIβ Peptide Applications :
Blocking Background :
Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type IIβ (sodium channel, voltage-gated, typeII, β), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type IIβ contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2. Alternative Name :
Sodium channel subunit beta-2; SCN2B; ORF Names: UNQ326/PRO386; Na+ CP typeIIβ Swiss-Prot :
O60939 Product :
1 mg/ml in DI water. Purification&Purity :
Synthetic peptide Na+ CP type IIβ. (Note: the amino acid sequence is proprietary). The purity is > 98%. Storage&Stability :
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity :
This peptide can be used with studies using BS5811 Na+ CP type IIβ pAb.
Blocking peptide available as BS5811PP